Kambo contains a number of active compounds (which are all peptides):

  • Dermorphin — a potent mu-opioid receptor agonist.

  • Deltorphin — a very potent delta-opioid receptor agonist.

  • Phyllomedusin — a tachykinin which affects the salivary glands, tear ducts, intestines, and bowels; it contracts the smooth muscles and contributes to a violent purge.

  • Phyllokinin (and phyllomedusin) — potent blood vessel dilators that also increase the permeability of the blood-brain barrier.

  • Phyllocaerulein — which stimulates the adrenal cortex and the pituitary gland, causes a fall in blood pressure, causes tachycardia, and has a potent action on the gastrointestinal smooth muscle, and stimulates gastric, biliary and pancreatic secretions.

  • Sauvagine — which stimulates the adrenal cortex, causes a long-lasting fall in blood pressure and causes intense tachycardia.

  • Adenoregulin — acts on the adenosine receptors.

  • Dermaseptin — a potent antimicrobial for both Gram-positive and Gram-negative bacteria, and antiviral for herpes simplex virus.

Scientific research has identified the peptides dermorphin and deltorphin in kambo as potent opioid peptides. Opioids are painkillers and opioid peptides bind to receptors on human cells which trigger a pain masking response. Dermorphin is amazingly 30-40 times stronger than morphine.



The Kambo I use is harvested by the Matses tribe.  The Matses live along the Javari River in the Upper Amazon, along the border of Brazil and Peru, where the frogs are plentiful.  It is carefully and ethically harvested; the frogs are not harmed during the process. The frogs are located in 70-100 ft. trees near the Igarapés (rainforest waterways) where they gather to sing and announce the rain. They are generally harvested at dawn by the Matses who locate them by singing and imitating their songs.

The frogs are very passive and do not react when picked up because they have no known predators. They are carefully tied by each leg with Palia (straw) strips into an “X” shape. Sometimes a shaman will massage the toes to encourage the secretion which is then carefully scraped off and left to dry on small sticks.  The frogs are “milked” at appropriately-spaced intervals, so they never need to be poked or “smoked” in order to stimulate secretion. They are then released and return to their habitat unharmed. The Palia leaves a tiny white line on each leg which stops anyone from harvesting the frog again until it has faded which takes at least 3 months. They are always treated with utmost care and respect, as the Matses believe that to harm the frog will anger the animal spirits that they reside along with in the jungle.  They have a deep respect and love for them, knowing they are our teachers and healers. 

Kambo collected in this way is considered 100% ethically harvested.  The funds they raise are shared among the 14 communities (approximately 3,200 Matses) residing on their extensive homeland.  This Kambo is clean, always fresh, and only the first secretions, which are stronger, are utilized.  The frogs are also then left with sufficient secretion to defend themselves from predators.  Every stick is properly wrapped and stored.  You can always be sure that I only use the very best, ethically harvested, medicine


The indigenous tribes say the main reason to receive the natural vaccine is to remove ‘Panema’ which is the thick cloud of haziness that sits on top of the energy field of a person. ‘Panema’ can also be translated as bad luck, laziness, depression, or confusion.  It is the state of being that attracts discomfort and disease. Kambo is said to remove ‘Panema’ and bring the person back to his/her natural state of perfect harmony and highest physical, emotional and spiritual potential, reconnecting one to self. 

According to the tribes, when nothing is going right in your life, it is the right moment to take Kambo. As well as this energetic clearing effect, Kambo has potent physical benefits also. Kambo is used as a traditional shamanic medicine to gain strength, maintain or regain health, and to provide immunity. The tribes, often times, apply it before hunting, in order to increase strength, improve vision and lend the hunters a ‘magical’ ability to locate prey. It is also used to cleanse the body of just about any illness, such as headaches, allergies, thyroid problems, arthritis, infections, addiction to pharmaceuticals, drugs, nicotine, alcohol, and so on. The tribes also use it for rainforest specific issues, such as malaria and snake and spider bites. Traditional Caboclo recommendation is to receive a full 3 applications of Kambo within one moon cycle (28 days) in order to achieve the full potential and for longer beneficial effects.

Kambo Points. Traditionally, Kambo points or secretion are referred to as "medicina"


Traditionally, Kambo points or secretion are referred to as "medicina"




Rapé is a tobacco snuff. It is a sacred shamanic tool, that has been used by tribes of the Amazon basin for thousands of years and is an essential part of their tribal culture and history. Rapé is the name for one of many of these snuffs, and it's foundation lies by numerous indiginous tribes in Acre, Brazil. Curiously, Rapé is administered (blown) into the nostrils with a special blowpipe called "Kuripe" (self administration) or "Tepi" (another person administers). This "blow" is quite forceful and not specifically pleasant.

The ashes that are the second important component in a Rapé come from the bark of a variety of medicinal or sacred trees. The production and choice of ashes and the exact composition and ratio of ingredients often remain a secret of the tribe. South American shamans use tobacco as a sacred, wholesome medicine and there exists a very close connection between tobacco use and shamanism that has little in common with our western way of tobacco use. Indigenous tribes use tobacco in ceremonies, to predict good weather, fishing, or harvest, and for spiritual (e.g. vision quest, trance etc) and curing purposes, but rarely for smoking. The use of tobacco by indigenous tribes in South America, such as the Kaxinawá, Nu-nu, Yawanawá, and Katukina, is profoundly entrenched in their culture, and has been employed at least since the Mayan civilization for ritual, medicinal and recreational purposes.


Using Tobacco snuff or Rapé has many different purposes for indigenous tribes, whereof female puberty rites, initiation rites, cashiri drinking festivals, social rites, and healing ceremonies. Yet, every tribe has their own routine: some apply it every day after breakfast and dinner, other tribes use it three times during the night. A typical Rapé ceremony involves a mutual administration by two persons. The Rapé is blown high up into the nostrils with a pipe made from bamboo or bone. The intense blow immediately focuses the mind, stops the “mind chattering” and opens the entire freed mindspace for your intentions.

Furthermore, this helps releasing emotional, physical, and spiritual illnesses and eases negativity and confusion, enabling a thorough grounding of the mind. Likewise, shamans use Rapé to re-align with their energy channels and with their higher self, and to intensify their connection with the world and the universe. In addition, Rapé paves the way for detoxifying the body and cleans out all excess mucus, toxins, and bacteria, thereby, assisting in fighting colds and snuffles. Moreover, Rapé stimulates the mind with its nicotinic content that in turn releases a.o. epinephrine, acetylcholine, and dopamine, supporting an increased focus, presence, and intuition.

Rapé could decalcify the pineal gland, which is involved in melatonin secretion,circadian time perception, and drug metabolism. Calcification of the pineal gland has been associated with neurodegenerative diseases, such as Alzheimer's disease, and fluoride exposure, which further stresses the importance of a healthy pineal gland. Yet, whether Rapé can really help the decalcification of the pineal gland, is highly debated and needs still to be scientifically proven.  

I offer Rapé during and after Kambo if needed.


The plant-based eye drops — brewed from the Tabernaemontana genus of shrubs native to the upper Amazon — are said to enhance eyesight and have long been used by indigenous tribes to prevent and treat ocular diseases like glaucoma, cataracts, near-sightedness and blindness.

But sananga is also commonly used to treat skin diseases, infections, arthritis, cancer, and perhaps most interestingly, to clear a person of what is called panema—anxiety, depression, bad luck, negative energies, and laziness. In fact, it’s by clearing this panema that sananga is said to promote overall eye health. As a shaman would explain it, sananga does its work not at the physical or cellular level but rather on an energetic level. While shamans may describe it as energetic healing, scientific studies dating to the 1970’s show that shrubs in the Tabernaemontana genus have a variety of pharmacological properties that could help explain sananga’s ability to foster healthy vision.

I offer sananga to clients to help them ground themselves before a Kambo treatment.



Kambo has no known detrimental side effects, so when it is responsibly administered, it is completely safe.  There are some people who should not take it; generally, it is not for you if you have, or have had in the past, any of the following conditions (This is not an exhaustive list):

  • Heart bypass surgery.

  • Enlarged heart.Implanted cardioverter defibrillators.

  • Congestive heart disease.

  • Excess fluid in the heart sack.

  • Heart valve replacement surgery.

  • Organ transplant.Active ulcers.Addison’s Disease.

  • Crohn’s Disease/Irritable Bowel Syndrome (IBS).

  • Brain hemorrhage.

  • Blood clots.

  • Serious mental health conditions, excluding depression, PTSD and anxiety.

  • Lack the mental capacity to decide to take Kambo.

  • Seriously low blood pressure that requires medication.

  • Anyone recovering from a major surgical procedure.

  • Pregnant or breastfeeding women with babies under 1-year old.

  • Within 21 days of giving birth.Under 18 years of age.

  • Chemotherapy or radiation treatments of less than 6 weeks prior or 6 weeks afterward.

* If you are asthmatic, be sure to bring your inhaler with you.

* Diabetics need to bring insulin, testing strips, and food.



  • People taking dieting or sleeping supplements.

  • Active drug or alcohol addiction.

  • Do not do water-fast for 7 days before or after taking Kambo.

  • Colonics, enemas, liver flushes, or any water-based detox should be avoided within 3 days before and after taking Kambo.

THIS IS NOT TO BE CONFUSED WITH THE WATER ONLY FASTING YOU WILL DO 10-12-HOURS PRIOR TO YOUR SESSION (you can have water, but not excessively, during this time).

You will be instructed to drink 2 liters of water about 15 minutes in my presence before I place the Kambo on.  It is STRONGLY ADVISED that you do not drink more than 5 liters of water during your session, including 2 hours before and after.

Do not consume alcohol or other recreational substances 24-48 hours before or after your Kambo session.



570. 534. 1826

  • Facebook

© 2020  mammakambo.com